- Country: Italy
- Summary: Evaluation of Microbiome-Relevant Biomarkers and in Vitro Models for Xenobiotic Risk Assessment
- ITT Ref No: 134411223
- Deadline: 12 Mar 2026
- Financier: European Food Safety Authority (EFSA)
- Purchaser Ownership: Government
- Tender Value: EUR 300000
- Notice Type: Tender
- Document Ref. No.: 54146-2026
- Purchaser's Detail:
- Description:
- Addressing a key knowledge gap identified in EFSA's Gut Microbiome Roadmap, the project aims to establish foundational methodological elements for assessing the potential adverse effects of dietary xenobiotics on the gut microbiome and host health through systematic available evidence appraisal and meta-synthesis. In particular, the project will systematically evaluate promising microbiome-relevant biomarkers related to key health endpoints (e.g. intestinal barrier integrity, inflammatory responses, microbiome metabolic capacity, immune system effects, microbiome composition and function) and the suitability of available in vitro models (e.g., SHIME, triple co-culture, MBRA, organoids). It will prioritise optimal biomarker-in vitro model pairings based on regulatory science applicability and feasibility, and identify appropriate analytical methods (including omics-based approaches) for each combination. The outcomes will provide an evidence-based prioritisation framework and feasibility assessment to inform potential follow-up experimental validation of the prioritised biomarker-in vitro model combinations and support the possible integration of microbiome data into risk assessment.
Doc Title: Evaluation of microbiome-relevant biomarkers and in vitro models for xenobiotic risk assessment
Contract Type: services - Documents:
Purchaser : EUROPEAN FOOD SAFETY AUTHORITY
Address: EFSA.ED.CSO - Chief Scientist Office
Town: Parma
NUTS-Code: ITH52
Postal Code: I-43126
Phone: +39 0521 036 111
Email :efsaprocurement@efsa.europa.eu
URL :https://www.efsa.europa.eu
Evaluation of Microbiome-Relevant Biomarkers and in Vitro Models for Xenobiotic Risk Assessment - Italy Tender
The EUROPEAN FOOD SAFETY AUTHORITY, a Government sector organization in Italy, has announced a new tender for Evaluation of Microbiome-Relevant Biomarkers and in Vitro Models for Xenobiotic Risk Assessment. This tender is published on ItalyTenders under ITT Ref No: 134411223 and is categorized as a Tender. Interested and eligible suppliers are invited to participate by reviewing the tender documents and submitting their bids before the deadline on 2026-03-12.
The estimated tender value is EUR 300000, and full details, including technical specifications and submission requirements, are provided in the official tender documents. Ensure all submissions meet the criteria outlined to be considered for evaluation.
